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Everything you need on your walk can now be held in one hand!
The all-in- one ergonomic design holds any dog leash and allows you to walk your dog with ease and comfort. You can customize me by adding any of my connectables. Hold everything you need to free your hands.
Supreme comfort: The soft silicone grip comfortably fits hands of all sizes. Super lightweight and easy to carry. The grip eliminates hand soreness and chafing commonly seen when holding leashes.
Leash carabiner: The specifically designed carabiner can hold any dog weighing up to 85lbs. Replace the standard carabiner with the extreme carabiner to walk a dog weighing more than 85lbs. Or replace the standard carabiner with my dual leash carabiner to freely walk two dogs in one hand. Recommended for a 3ft leash or shorter.
Freedom: The sliding and pivoting carabiner absorbs your dog's abrupt movements, offering an amazing sense of freedom. Pulling and tugging become more manageable with the patented rail sliding system.
"p"Multi-function button: use the multi-function button for many things. You can pair the button with one of my connectables, to change function. "p"Poop bag dispenser connectable (included): Easily hold one standard poop bag roll. Tearing a poop bag is easy with the exceptional pull and tear design. Hinge the poop bag under my clip so you don't have to carry the mess.
Iâm your Gismo starter kit. My all-in-one ergonomic design allows you to walk your dog with ease and comfort.
Iâm your everything. Iâm the new and innovative, connectable dog walking device that changes everything. My all-in-one ergonomic design holds any dog leash and allows you to walk your dog with ease and comfort. You can customize me by adding any of my connectables. You see, I hold everything you need to free your hands.
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Supreme Comfort"p" My soft silicone grip comfortably fits hands of all sizes. I am super lightweight and easy to carry. My grip eliminates hand soreness and chafing commonly seen when holding leashes. |
Leash Carabiner"p" My German engineered carabiner can hold any dog leash. I recommend a 4ft leash or shorter to walk with me. Replace me with my split carabiner to freely walk two dogs in one hand. |
Freedom"p" My sliding and pivoting carabiner absorbs your dogâs abrupt movements, offering an amazing sense of freedom. Pulling and tugging become more manageable with my patented rail sliding system for your dog leash. |
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Poop Bag Dispenser"p" I am your poop bag dispenser. I easily hold one standard poop bag roll. Tearing a poop bag is easy with my exceptional pull and tear design. |
Poop Bag Clip"p" I will help you carry a used poop bag. Hinge the poop bag under my clip so you donât have to carry the mess. |
Multi-Function Button"p" Use my multi-function button for many things. You must pair my button with one of my connectables, and it will change my function. |
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Founded in 2006, Dog Gone Smart Pet Products focus is on developing high quality products and solutions for the pet industry using innovative and advanced technologies. Our goal is to make pet parenting more fun with less stress.
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Dog Gone Smartâs classic style bedding and apparel are finished with Repelz-it nano technology. Repelz-It prevents liquids, dirt and natural oil in your petâs coat from sticking to Dog Gone Smart fabrics. Repelz-It also uses a safe, state-of-the-art bacteriostatic, which inhibits the spread of certain odor-causing pathogens.
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Innovation, design and comfort for you and your pet combine in all of our products. From our beds and cushions to i'm Gismo, our all-in-one modular leash and outerwear with Meteor reflective technology, everything we make, makes your life easier, safer and better.
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Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.16
Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs;
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Top 10 cited articles
Top 10 cited articles
No. | Cited items | Category | Citations |
1 | What Is New in Rome IV Max J Schmulson, and Douglas A Drossman. Journal of Neurogastroenterology and Motility. 2017 May; 23(2): 151-163. |
Review | 219 |
2 | Panini Premier League 2021 Sticker Collection (x100 Packs) Karol Kowalski, and Agata Mulak. J Neurogastroenterol Motil. 2019 Jan; 25(1): 48-60. |
Review | 202 |
3 | Pharmacokinetics and Pharmacodynamics of the Proton Pump Inhibitors Jai Moo Shin, and Nayoung Kim. Journal of Neurogastroenterology and Motility. 2013 Jan; 19(1): 25-35. |
Review | 173 |
4 | Biopsychosocial Model of Irritable Bowel Syndrome Yukari Tanaka, Motoyori Kanazawa, Shin Fukudo and Douglas A Drossman. J Neurogastroenterol Motil. 2011 Apr; 17(2): 131-139. |
Review | 157 |
5 | Epidemiology of Gastroesophageal Reflux Disease in Asia: A Systematic Review Hye-Kyung Jung. J Neurogastroenterol Motil. 2011 Jan; 17(1): 14-27. |
Review | 136 |
6 | Modulatory Effects of Gut Microbiota on the Central Nervous System: How Gut Could Play a Role in Neuropsychiatric Health and Diseases Shadi S Yarandi, Daniel A Peterson, Glen J Treisman, Timothy H Moran, and Pankaj J Pasricha. J Neurogastroenterol Motil. 2016 Apr; 22(2): 201-212. |
Review | 129 |
6 | Effect of Probiotics on Central Nervous System Functions in Animals and Humans: A Systematic Review Huiying Wang, In-Seon Lee, Christoph Braun, and Paul Enck. Journal of Neurogastroenterology and Motility. 2016 Oct; 22(4): 589-605. |
Review | 129 |
8 | Achalasia Cardia Subtyping by High-Resolution Manometry Predicts the Therapeutic Outcome of Pneumatic Balloon Dilatation Nitesh Pratap, Rakesh Kalapala, Santosh Darisetty, Nitin Joshi, Mohan Ramchandani, Rupa Banerjee, Sandeep Lakhtakia, Rajesh Gupta, Manu Tandan, G V Rao and D Nageshwar Reddy. J Neurogastroenterol Motil. 2011 Jan; 17(1): 48-53. |
Original Article | 127 |
9 | How to Interpret Hydrogen Breath Tests Uday C Ghoshal. J Neurogastroenterol Motil. 2011 Jul; 17(3): 312-317. |
How to Interpret a Functional or Motility Test | 123 |
10 | The Immune System in Irritable Bowel Syndrome Giovanni Barbara, Cesare Cremon, Giovanni Carini, Lara Bellacosa, Lisa Zecchi, Roberto De Giorgio, Roberto Corinaldesi and Vincenzo Stanghellini. J Neurogastroenterol Motil. 2011 Oct; 17(4): 349-359. |
Review | 119 |
Twin Size Linen Upholstered Platform Bed with Headboard and Two